Acetylcholine, Dopamine, and Glutamate measured in three brain areas with a new SPME-probe

Our new paper shows reliable Multi-Neuromodulator measurements in the awake nonhuman primate in prefrontal cortex, premotor cortex and the basal ganglia using a new chemical sensing probe. The probe uses principles of Solid-Phase-Microextraction and is a development by the SPME pioneer and collaborator Prof. Janusz Pawliszyn from the University of Waterloo. The paper can be downloaded here.

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We hosted a superb 2018 CPPC (Computational Properties of Prefrontal Cortex) Workshop at Vanderbilt. The workshop attracted more than 60 emerging and established (neuro-)scientists about how the prefrontal cortex works – See the program and more at the www link CPPC2018. This year had special sessions on value-based decision making and uncertainty, social cognition, functional […]

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A recent paper provides rare causal evidence that phase-specific stimulation during beta oscillation bursts lead to transient changes in effective (latent) connectivity. This finding and its potentially widespread implications are discussed in our paper Womelsdorf T, Hoffman K (2018) Latent Connectivity: Neuronal Oscillations Can Be Leveraged for Transient Plasticity. Current Biology. 28(16):R879-R882..

Theta and Beta Frequency

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