Striatum interneurons track learning of attention cues

Our new paper shows how fast spiking interneurons in the striatum activate specifically when attention cues are learned. This is a rare paper where we succeed to isolate fast spiking interneurons in recordings from nonhuman primate anterior striatum while the animals performed a complex feature-based attentional learning task. Phd can. Kia Banaeie Boroujeni spearheaded the advanced analysis pipeline for this sophisticated paper – congratulations for a huge milestone in deciphering the sources of attentional control! The paper can be downloaded here. See also Research-News @ Vanderbilt covering these findings.

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Fronto-Striatal Circuits Optimize Feature-based Attention and Learning

Our new publication (Oemisch et al. (2018) Feature Specific Prediction Errors and Surprise across Macaque Fronto-Striatal Circuits during Attention and Learning) provides the first 4-brain-area survey of how prediction error information in the anterior cingulate – ventral striatum and lateral prefrontal – caudate fronto-striatal loops relate to feature-based attention and learning. We found prediction errors […]

Updating of Attentional Priorities is supported by Noradrenergic Receptors

Our new paper shows that the flexible learning of attention sets is facilitated by noradrenergic receptor action. The paper “Noradrenergic alpha-2a receptor stimulation enhances prediction error signaling and updating of attention sets in anterior cingulate cortex and striatum” is published in Nature Communications was led by PhD alumnus Ali Hassani and found that neuronal firing […]

Computational Properties of Prefrontal Cortex – Workshop

We hosted a superb 2018 CPPC (Computational Properties of Prefrontal Cortex) Workshop at Vanderbilt. The workshop attracted more than 60 emerging and established (neuro-)scientists about how the prefrontal cortex works – See the program and more at the www link CPPC2018. This year had special sessions on value-based decision making and uncertainty, social cognition, functional […]