Acetylcholine, Dopamine, and Glutamate measured in three brain areas with a new SPME-probe

Our new paper shows reliable Multi-Neuromodulator measurements in the awake nonhuman primate in prefrontal cortex, premotor cortex and the basal ganglia using a new chemical sensing probe. The probe uses principles of Solid-Phase-Microextraction and is a development by the SPME pioneer and collaborator Prof. Janusz Pawliszyn from the University of Waterloo. The paper can be downloaded here.

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A Novel Monkey Kiosk: Cognitive Enrichment and Cognitive Assessment

We now published the hardware and software design for a novel Monkey Kiosk Station that provides cognitive enrichment and the ability to assess cognition with cage-based touchscreen tasks. The paper and its appendix with the technical details are available here.

Adaptive Learning needs Attention, Meta-learning and Working Memory

We tested which model mechanisms best explain how six animals learn attention sets and found a common set of most-important behavioral mechanisms that account for learning success.When learning attention sets is easy value based reinforcement learning and working memory are powerful, but when learning problems are more complex learning is more efficient with attention and […]

Phase-specific Activation Induces Latent Connectivity Changes

A recent paper provides rare causal evidence that phase-specific stimulation during beta oscillation bursts lead to transient changes in effective (latent) connectivity. This finding and its potentially widespread implications are discussed in our paper Womelsdorf T, Hoffman K (2018) Latent Connectivity: Neuronal Oscillations Can Be Leveraged for Transient Plasticity. Current Biology. 28(16):R879-R882..