Striatum interneurons track learning of attention cues

Our new paper shows how fast spiking interneurons in the striatum activate specifically when attention cues are learned. This is a rare paper where we succeed to isolate fast spiking interneurons in recordings from nonhuman primate anterior striatum while the animals performed a complex feature-based attentional learning task. Phd can. Kia Banaeie Boroujeni spearheaded the advanced analysis pipeline for this sophisticated paper – congratulations for a huge milestone in deciphering the sources of attentional control! The paper can be downloaded here. See also Research-News @ Vanderbilt covering these findings.

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A recent paper provides rare causal evidence that phase-specific stimulation during beta oscillation bursts lead to transient changes in effective (latent) connectivity. This finding and its potentially widespread implications are discussed in our paper Womelsdorf T, Hoffman K (2018) Latent Connectivity: Neuronal Oscillations Can Be Leveraged for Transient Plasticity. Current Biology. 28(16):R879-R882..

Inter-areal neural routing states emerge and switch during oscillatory bursts and with attention

We have a new major finding published at Neuron. We found that spiking in different areas (ACC, Striatum, LPFC) engage in ~20ms wide correlations, and that this coordinated activity has systematic time lags that correspond to the anatomical connectivity. These ‘baseline routing states’ are amplified during beta bursts, and switch directionality (between ACC and PFC) […]

The phase of firing of fronto-striatal neurons encodes learning variables

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