Phase-specific Activation Induces Latent Connectivity Changes

A recent paper provides rare causal evidence that phase-specific stimulation during beta oscillation bursts lead to transient changes in effective (latent) connectivity. This finding and its potentially widespread implications are discussed in our paper Womelsdorf T, Hoffman K (2018) Latent Connectivity: Neuronal Oscillations Can Be Leveraged for Transient Plasticity. Current Biology. 28(16):R879-R882..

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Fronto-Striatal Circuits Optimize Feature-based Attention and Learning

Our new publication (Oemisch et al. (2018) Feature Specific Prediction Errors and Surprise across Macaque Fronto-Striatal Circuits during Attention and Learning) provides the first 4-brain-area survey of how prediction error information in the anterior cingulate – ventral striatum and lateral prefrontal – caudate fronto-striatal loops relate to feature-based attention and learning. We found prediction errors […]

First Neuropharmacological Contribution

Congratulations to Ali and Mariann for the first neuropharmacological contribution from our laboratory with the article A computational psychiatry approach identifies how alpha-2A noradrenergic agonist Guanfacine affects feature-based reinforcement learning in the macaque . This study first surveys all 14 different tasks that have ever been used with Guanfacine in nonhuman primate studies and than […]